Publications

2026
[1] N Kadivar, G Li (equal first author)*, J Zheng, M Dao, GE Karniadakis, M Xu. An AI-enabled tool for quantifying overlapping red blood cell sickling dynamics in microfluidic assays. arXiv:2601.17703, 2026. [Open Access]
Paper 1 figure
2025
[2] Z Chai, G Li*, PA Ndour, P Connes, PA Buffet, M Franco, GE Karniadakis. In silico biophysics and rheology of blood and red blood cells in Gaucher Disease. PLoS Computational Biology, 21(9): e1012705, 2025. [Open Access]
Paper 2 figure
[3] Y Chang, G Li(equal first author)*, J Sim, GE Karniadakis, RR Zhao. Clot Treatment via Spinning-Induced Fibrin Microstructure Densification and Clot Volume Reduction. Extreme Mechanics Letters (2025): 102391. [Open Access]
Paper 3 figure
2024
[4] Guansheng Li*, He Li, Papa alioune Ndour, Mélanie Franco, Xuejin Li, Ian MacDonald, Ming Dao, Pierre A Buffet, George Em Karniadakis. Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics. Computers in Biology and Medicine 182 (2024): 109198. [Open Access]
Paper 4 figure
[5] Yu Zhang, Yuhao Qiang, He Li, Guansheng Li*, Lu Lu, Ming Dao, George E Karniadakis, Aleksander S Popel, Chen Zhao. Signaling-biophysical modeling unravels mechanistic control of red blood cell phagocytosis by macrophages in sickle cell disease. PNAS Nexus 3.2 (2024): pgae031. [Open Access]
Paper 5 figure
2023
[6] G Li*, Y Qiang, H Li, X Li, PA Buffet, M Dao, GE Karniadakis. A combined computational and experimental investigation of the filtration function of splenic macrophages in sickle cell disease. PLOS Computational Biology 19(12), e1011223. [Open Access]
Paper 6 figure
[7] G Li*, T Ye, Z Xia, S Wang, Z Zhu. Analysis and prediction of hematocrit in microvascular networks. International Journal of Engineering Science 191, 103901. [Open Access]
Paper 7 figure
[8] Ander Dorken-Gallastegi, Yao Lee, Guansheng Li*, He Li, Leon Naar, Xuejin Li, Ting Ye, Elizabeth Van Cott, Rachel Rosovsky, David Gregory, Ronald Tompkins, George Karniadakis, Haytham MA Kaafarani, George C Velmahos, Jarone Lee, Galit H Frydman. Circulating cellular clusters are associated with thrombotic complications and clinical outcomes in COVID-19. iScience 26(7). [Open Access]
Paper 8 figure
[9] G Li*, Y Qiang, H Li, X Li, M Dao, GE Karniadakis. In silico and in vitro study of the adhesion dynamics of erythrophagocytosis in sickle cell disease. Biophysical Journal 122(12), 2590-2604. [Open Access]
Paper 9 figure
[10] G Li*, T Ye, B Yang, S Wang, X Li. Temporal-spatial heterogeneity of hematocrit in microvascular networks. Physics of Fluids 35(2). [Open Access]
Paper 10 figure
2021
[11] S Wang, T Ye, Guansheng Li*, X Zhang, H Shi. Margination and adhesion dynamics of tumor cells in a real microvascular network. PLoS Computational Biology 17(2), e1008746. [Open Access]
Paper 11 figure
2020
[12] T Ye, X Zhang, Guansheng Li*, S Wang. Biomechanics in thrombus formation from direct cellular simulations. Physical Review E 102(4), 042410. [Open Access]
Paper 12 figure
[13] Guansheng Li*, T Ye, S Wang, X Li, R UI Haq. Numerical design of a highly efficient microfluidic chip for blood plasma separation. Physics of Fluids 32(3), 031903. [Open Access]
Paper 13 figure
[14] Guansheng Li*, T Ye, X Li. Parallel modeling of cell suspension flow in complex micro-networks with inflow/outflow boundary conditions. Journal of Computational Physics 401, 109031. [Open Access]
Paper 14 figure
2019
[15] T Ye, L Peng, Guansheng Li*. Red blood cell distribution in a microvascular network with successive bifurcations. Biomechanics and Modeling in Mechanobiology 18(6), 1821-1835. [Open Access]
Paper 15 figure